All time favorites are Spirited Away, Howl's Moving Castle, Whisper of the Heart, Dual!, Suzuka, Love Hina, Neon Genesis Evangelion, anything Tenchi, everything Full Metal Panic!, Beck, and a whole lot of other stuff.
I'm currently watching Vandread, but I have been only slowly going through the episodes.
I'm looking forward to seeing Rumbling Hearts season 2, Bacanno! and possibly Bokurano (appears to me like it's the next Neon Genesis Evangelion). I have a very long list I want to watch, but I doubt I'll ever get around to seeing all of them.
Favorite manga are Beck: Mongolian Chop Squad, Suzuka, Love Hina, Ichigo 100%, Video Girl AI and I's. I'm more into romance manga than stuff like the Naruto and Bleach manga. They don't grip me as much.
A more in depth look for me.